This is the change in conformation that is associated with protease resistance and the accumulation of insoluble aggregates of prion protein.
Research The abnormal prion protein causing vCJD remains a scientific enigma.
The prion hypothesis states that it is due to differences in the chemical or tertiary structure of the prion hypothesis states that it is due to differences in the chemical or tertiary structure of the prion protein.
Research on human tissues has confirmed that people of all genetic types can have the rogue prion protein responsible for the disease.
Other yet undiscovered genes outside the prion protein gene locus might also confer susceptibility.
