Tissue Plasminogen Activator Definition

noun
A clot-dissolving enzyme that is produced naturally by cells in the walls of blood vessels and catalyzes the conversion of plasminogen to plasmin.
American Heritage Medicine
An enzyme produced by the blood vessels that dissolves blood clots by converting plasminogen into plasmin: it is manufactured using recombinant DNA technology and used to prevent stroke, etc.
Webster's New World
Synonyms:

Tissue Plasminogen Activator Sentence Examples

  • One such drug is called tissue plasminogen activator (alteplase) which is a clot-dissolving drug not yet in common use in the UK.

  • The majority of data are from trials using recombinant tissue plasminogen activator (rt-PA ), also known as alteplase.

  • Clot-busting medications, such as tissue plasminogen activator (t-PA, also called streptokinase enzymes or thrombolytic drugs), may be given to help dissolve the renal clot.

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