There was a temple of Serapis at Portus.
Later, however, as in the Commentary on this work written by Synesius to Dioscorus, priest of Serapis at Alexandria, which probably dates from the end of the 4th century, a changed attitude becomes apparent; the more practical parts of the receipts are obscured or omitted, and the processes for preparing alloys and colouring metals, described in the older treatise, are by a mystical interpretation represented as resulting in real transmutation.
The cult of Anubis must at all times have been very popular in Egypt, and, belonging to the Isis and Serapis cycle, was introduced into Greece and Rome.
Here were represented Isis and Serapis, Helios, the Mother of the Gods, the Fates, Demeter and Persephone; but no trace of these temples remains.
One figure called Sarapo appears to be the Egyptian Serapis, and others are perhaps Babylonian deities.