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Severe combined immunodeficiency (SCID) is the most serious primary or congenital human immunodeficiency disorder.
Children with SCID are vulnerable to recurrent severe infections, retarded growth, and early death.
In children with SCID, the immune system does not function properly because T, B, and NK cells are either absent or defective.
Several different immune system disorders are grouped under SCID.
Children with X-linked SCID have low T-cell and natural killer (NK) cell levels but elevated B-cell levels.
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