The mining operations are chiefly centred in the Sierra Mojada, Sierra Carmen, and in the Santa Rosa valley.
Among the public buildings are several churches and hospitals (including the Jurujuba yellow-fever hospital and the Barreto isolation hospital), the government palace, a municipal theatre and a large Salesian college situated in the suburbs of Santa Rosa on an eminence overlooking the lower bay.
South of the entrance to Pisco Bay is Zarate Island, and farther south the white level islet of Santa Rosa.
The federal palace and the church of Santa Rosa are examples of the work of the celebrated Mexican architect, Francisco Eduardo de Tresguerras (1765-1833), who restored the church of Santa Clara also.
Gold is obtained at Las Quebradas near Izabal, silver in the departments of Santa Rosa and Chiquimula, salt in those of Santa Rosa and Alta Vera Paz.