MPS I Definition

noun
Any of several types of mucopolysaccharidosis characterized by the presence of dermatan sulfate and heparan sulfate in the urine, usually divided into a severe type known as Hurler syndrome (MPS IH), an attenulated type known as Scheie syndrome (MPS IS), and an intermediate type known as Hurler-Scheie syndrome (MPS IH/S).
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MPS I Sentence Examples

  • This tends to be the most severe form of MPS I.

  • They can have normal intelligence; however, some individuals with MPS I H/S experience learning difficulties.

  • The prognosis for children with MPS I H/S is variable with some individuals dying during childhood, while others live to adulthood.

  • Scheie syndrome is the mild form of MPS I.

  • Individuals with MPS I S usually have normal intelligence, although there have been some reports of individuals with MPS I S developing psychiatric problems.

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