Hirschsprung-s-disease Definition

Hirschsprung-s-disease Sentence Examples

• Children diagnosed with Hirschsprung's disease lack nerve cells (ganglia) in the large intestine, severely affecting the wavelike movements that propel material through the colon.

• Symptoms can be removed in at least 90 percent of children born with Hirschsprung's disease.

• Motility disorders such as Hirschsprung's disease and psuedo-obstruction may cause blockages by retarding peristalsis, the intestinal muscle contractions that move food and waste.

• Proof that genetic factors contribute to Hirschsprung's disease is that it is known to run in families, and it has been seen in association with some chromosome abnormalities.

• Molecular diagnostic techniques have identified many genes that cause susceptibility to Hirschsprung's disease.