There is very little grey matter in the cortex of the hemispheres, the surface of which is devoid of convolutions, mostly quite smooth; in others, for instance pigeons, fowls and birds of prey, a very slight furrow might be compared with the Sylvian fissure.
Large doses also depress the nervous system, weakening the anterior horns of grey matter in the spinal cord so as ultimately to cause complete paralysis, and also causing a partial insensibility of the cutaneous nerves of touch and pain.
This continuum was held to render possible conduction in all directions throughout the grey matter of the whole nervous system.
At present we say of such a substance as thebaine, " it acts on the anterior cornua of grey matter in the spinal cord," but why on them and not elsewhere we do not know.
These bodies stimulate the grey matter in the spinal cord and cause tetanic convulsions.