In the Yale Divinity School his influence was powerful, and in 1833 one of his foremost opponents, Bennet Tyler (1783-1858), founded in East Windsor a Theological Institute to offset Taylor's teaching at Yale.
From 1872 until his death he was Bussey Professor of New Testament Criticism and Interpretation in the Harvard Divinity School.
When he entered the divinity school he was an orthodox Unitarian; when he left it, he entertained strong doubts about the infallibility of the Bible, the possibility of miracles, and the exclusive claims of Christianity and the Church.
Subsequently he took a degree in divinity at the Harvard Divinity School.
He graduated at Amherst in 1839 and at the Harvard Divinity School in 1842.