His first work was an inquiry into the authorship of the Commentary on St Paul's Epistles and the Treatise on Biblical Questions, ascribed to Ambrose and Augustine respectively.
Justina was an Arian, and the imperial court at Milan pitted itself against the Catholics, under the famous Ambrose, bishop of that city.
He was condemned by a Roman synod under Bishop Siricius in 390, and afterwards excommunicated by another at Milan under the presidency of Ambrose.
Certain peculiarities introduced by St Ambrose distinguish the ritual of Milan from that of the general church.
St Cyprian, St Ambrose and St Augustine, St Paulinus of Nola and St John Chrysostom had practised law as teachers or advocates.