The new duke of Urbino was the Lorenzo de' Medici to whom Machiavelli addressed The Prince.
Leo had intended his younger brother Giuliano and his nephew Lorenzo for brilliant secular careers.
Some of the nominations were excellent, such as Lorenzo Campeggio, Giambattista Pallavicini, Adrian of Utrecht, Cajetan, Cristoforo Numai and Egidio Canisio.
Thus he gave to his undeserving son Franceschetto several towns near Rome and married him to the daughter of Lorenzo de' Medici.
Thus was elaborated the type of despot which attained completeness in Gian Galeazzo Visconti and Lorenzo de Medici.